Plain-English translation of NCT05890781 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are building special laboratory models called immune organoids using cells from children and young adults diagnosed with certain cancers—including brain tumors, kidney tumors, neuroblastoma, and sarcomas. These models are grown from patient tissue samples in the lab to help scientists understand how the immune system works against these cancers. By studying these models, researchers hope to develop better treatments in the future.
Pediatric cancers are difficult to treat, and doctors need better ways to understand how each patient's immune system responds to their specific cancer. This research aims to create personalized laboratory models that could eventually help design more targeted and effective treatments.
You likely qualify if…
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If you join this study, researchers will collect tissue samples from your cancer or tumor—likely during a biopsy or surgery you may already need for your diagnosis or treatment. These samples will be used to create laboratory models in the lab; you will not receive any direct treatment from this study itself. Your participation helps scientists learn more about how to fight these cancers in future patients.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
France
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris
Enrollment target
~108 participants
Started
May 2023
Primary completion
May 2028
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Claudia PASQUALINI, MD
Gustave Roussy, Cancer Campus, Grand Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.