Plain-English translation of NCT05899439 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 1 Diabetes research guide →Researchers want to understand why the immune system attacks the insulin-producing cells in the pancreas in type 1 diabetes. This study will collect blood samples from about 2,800 people—some who have type 1 diabetes and some who don't—to identify the immune signals and cell behaviors that lead to disease development.
Type 1 diabetes happens when the immune system mistakenly destroys pancreatic cells, but scientists don't fully understand how or why this happens. This research aims to identify the early warning signs and immune system changes that occur before and during the disease, which could eventually help prevent or catch type 1 diabetes earlier.
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If you join this study, you would have blood drawn by a healthcare provider—similar to a routine blood test. The researchers will analyze your blood to look at immune cells and markers related to type 1 diabetes. The study includes people of all ages, from infants to older adults, and participation is open to both those living with type 1 diabetes and those without it.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Sponsor
University of Florida
Collaborators
Juvenile Diabetes Research Foundation, National Institute of Allergy and Infectious Diseases (NIAID)
Enrollment target
~2,800 participants
Started
January 2005
Primary completion
January 2085
Age range
0 Years – 100 Years
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jennifer L Hosford, MPH
University of Florida
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.