Testing a new medication for people with stable sickle cell disease

This trial is testing a medication called fostamatinib to see if it is safe and tolerable for people with sickle cell disease. The medication works by blocking a protein involved in inflammation and cell damage. Researchers will monitor participants closely to understand how the body handles this medication and whether it might reduce symptoms.

Sickle cell disease causes serious pain and organ damage due to inflammation and abnormal blood cell behavior. This medication targets the inflammatory processes underlying the disease, so researchers want to find out if this treatment approach is safe and could help patients.