Plain-English translation of NCT05904132 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called closed-loop transcranial alternating current stimulation (tACS) — a non-invasive way to stimulate the brain using gentle electrical currents applied to the scalp. Researchers believe this treatment may help improve memory and thinking abilities in people with mild cognitive impairment, which often develops into Alzheimer's disease. The study will compare the real treatment to a placebo (a sham treatment) to see if it actually works.
Current treatments for early-stage memory loss and Alzheimer's disease are limited. This trial exists to explore whether this new brain stimulation approach can enhance the brain's natural rhythms and improve cognitive function before more severe dementia develops.
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You would visit the research center multiple times for study sessions. At each visit, researchers will place electrodes on your scalp to deliver mild electrical stimulation and record your brain activity using EEG (a test that measures brain waves). You'll also complete some memory and thinking tests on a computer and answer questions about your cognitive health. Some participants will receive the actual brain stimulation treatment, while others will receive a placebo, but researchers will personalize the treatment based on your individual brain activity patterns.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States