Plain-English translation of NCT05914766 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The PATHWAYS study is testing a supportive care program designed specifically for people recently diagnosed with locally advanced rectal cancer who are about to start multimodality treatment (which typically includes chemotherapy, radiation, and surgery). The program includes four one-on-one coaching sessions with a study clinician who provides information and emotional support, along with comprehensive educational materials to help you navigate your treatment journey.
Patients with advanced rectal cancer often face complex treatment plans and significant physical and emotional challenges. This study exists to see whether personalized coaching and education can help patients feel more prepared, confident, and supported as they manage their treatment and maintain their quality of life during this difficult time.
You likely qualify if…
You likely don't qualify if…
If you are assigned to the coaching group, you will have four individual sessions with a study clinician who will help you understand your treatment plan and support you emotionally. You will also receive comprehensive educational materials and workbooks to use at home. If you are assigned to the comparison group, you will receive an information resource guide. The study will follow you as you go through your cancer treatment to see whether the coaching helps you feel more confident and maintain a better quality of life.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Enrollment target
~80 participants
Started
September 2023
Primary completion
May 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kelsey Lau-Min, MD, MSCE
Massachusetts General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.