Plain-English translation of NCT05916638 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to better understand why sarcoidosis and tuberculosis cause similar inflammation patterns in the body, even though they have different causes. This study will collect blood samples from people diagnosed with either condition to examine specific immune cells called monocytes and macrophages. By studying these cells, scientists hope to find new ways to diagnose and treat both diseases more effectively.
Sarcoidosis and tuberculosis look very similar under a microscope and can be confused with each other, making diagnosis difficult. Currently, steroids are the main treatment, but doctors don't fully understand what causes the chronic inflammation in sarcoidosis. This research aims to identify what drives these immune cells to become overactive, which could lead to better treatments.
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You will visit a research clinic where doctors will take a blood sample to study your immune cells. The study compares samples from people with sarcoidosis and tuberculosis to understand how their immune systems respond differently. You will likely have one or a few visits depending on the study design, and the main thing required is a blood draw — no medications to take or long-term commitment.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
France
Enrollment target
~100 participants
Started
January 2024
Primary completion
January 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Karim Sacre, MD-PhD, PU-PH
Assistance Publique - Hôpitaux de Paris
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.