Plain-English translation of NCT05917795 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing endoscopic sleeve gastroplasty with Endomina®, a minimally invasive procedure performed through the mouth (without surgical cuts) that reshapes the stomach to help people lose weight. The study focuses on patients with end-stage kidney disease who are waiting for a kidney transplant but are currently ineligible because their weight is too high. Researchers want to see if this procedure can help patients reach a healthy weight so they can move forward with transplantation.
Many patients with kidney failure are ready for transplants but are turned away because they are overweight, which increases surgical risks. This trial exists to find out whether this newer, less invasive weight loss procedure can safely help these patients lose enough weight to become transplant candidates without needing major abdominal surgery.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo the endoscopic sleeve gastroplasty procedure, which is performed under anesthesia and reshapes your stomach to help you feel full faster. You will then be followed closely for 12 months before your transplant surgery and for another 12 months after transplantation. During these visits, doctors will monitor your weight loss, overall health, quality of life, and how well the procedure worked to help you reach transplant eligibility.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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