Plain-English translation of NCT05918835 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing a treatment called repetitive transcranial magnetic stimulation (rTMS)—a non-invasive procedure that uses magnetic pulses to stimulate specific areas of the brain. Researchers believe that certain patterns of brain activity in people with anorexia nervosa may drive the urge to restrict food, especially fatty foods. This study will test whether rTMS can help change those brain patterns and make it easier for people to eat normally.
Current treatments for anorexia nervosa don't work well enough for many adults, partly because we don't fully understand the brain mechanisms driving extreme food restriction. This study aims to understand how the brain controls food choices in anorexia nervosa and whether targeting specific brain regions with this treatment can help reduce the urge to restrict food.
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As an inpatient at the hospital's eating disorder program, you would receive either real or sham (placebo) brain stimulation sessions—neither you nor the researchers will know which one you're getting. The stimulation involves brief magnetic pulses applied to your scalp over a few sessions. You'll also complete brain imaging scans and use a computer to make food choices while your brain activity is measured. The entire study involves individualized treatment sessions and assessments designed to understand how your brain responds to the stimulation.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States
Sponsor
New York State Psychiatric Institute
Collaborators
National Institute of Mental Health (NIMH), National Eating Disorders Association
Enrollment target
~72 participants
Started
April 2023
Primary completion
June 2027
Age range
18 Years – 35 Years
Sex
Female only
Last updated on clinicaltrials.gov in July 2026.
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Central contact
Alexandra F Muratore, PhD
New York Sate Psychiatric Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.