Plain-English translation of NCT05920824 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →Researchers are studying heart valve leaks that develop in people with atrial fibrillation (an irregular heartbeat). This trial will help doctors understand why some people develop these leaks, how they progress over time, and what might predict who will have worse outcomes. By enrolling 141 patients, the study aims to identify different patterns of valve disease and the factors that influence how severe the condition becomes.
Valve leaks related to atrial fibrillation are not well understood — doctors don't know enough about why they happen, how they progress, or which patients are at highest risk. This study aims to fill that gap so that doctors can better predict and manage the condition in the future.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be followed for at least one year. You will have heart ultrasound images taken to measure your valve function, and researchers will track changes in your valve disease and any heart-related hospital visits. You may also complete questionnaires about your symptoms and activity level. The study takes place at St Bartholomew's Hospital in their outpatient clinics.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United Kingdom
Barts & The London NHS Trust
Enrollment target
~60 participants
Started
August 2023
Primary completion
August 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jawza Aldakhil
Barts & The London NHS Trust
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.