Plain-English translation of NCT05922202 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at how frailty—a condition of physical weakness and vulnerability—affects heart health and survival in people with COPD (chronic obstructive pulmonary disease, a serious lung condition). Researchers want to understand whether people with COPD who are also frail face higher risks of heart problems and death compared to people with COPD who are physically stronger.
Many people with COPD also develop heart problems, but doctors don't fully understand how physical weakness plays a role in that risk. This research aims to fill that gap so that treatment can be better tailored to people living with both conditions.
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As a participant, you would visit the clinic as an outpatient and have your physical strength assessed using a simple nine-point frailty scale. You would also complete a brief cognitive (thinking and memory) test. The research team would follow your health over 24 months with check-ins at 12 and 24 months to see how you are doing and whether any heart events or health changes occur.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
Italy
Collaborators
Campus Bio-Medico University, Ospedale Sant'Andrea - Azienda Sanitaria Locale di Vercelli-Reparto di Pneumologia
Enrollment target
~300 participants
Started
February 2024
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
40 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alessia Verduri, PhD
Respiratory Unit-University of Modena (Italy) - Hospital Policlinico Modena
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.