Plain-English translation of NCT05923073 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn's Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a medication called to see if it can help children and teenagers with moderate to severe Crohn's disease. The medication works by targeting a specific part of the immune system that causes inflammation in the intestines. Researchers want to find out if the treatment helps reduce symptoms and allows the intestines to heal.
Many children with Crohn's disease don't respond well to existing treatments, or they stop working over time. This medication works in a new way, and doctors hope it may help kids whose current treatments aren't working.
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The trial lasts about one year. First, you'll receive either as an IV infusion or injection under the skin for 12 weeks to see if it helps. At week 12, if you're responding well, you'll be randomly assigned to continue on one of two maintenance schedules (still as injections) for another 36 weeks. Throughout the trial, you'll have regular visits, blood tests, and possibly another camera test of your intestines to check how you're doing.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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