Plain-English translation of NCT05923073 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn's Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether a medication called can help children and teens with moderate to severe Crohn's disease feel better and heal their intestines. works by blocking a specific protein involved in inflammation. The study will track whether the medication helps reduce symptoms and heal the gut over one year.
Many children with Crohn's disease don't respond well to current treatments, or their symptoms return over time. This trial is testing whether this new medication — which works differently than older treatments — can offer better and longer-lasting relief.
You likely qualify if…
You likely don't qualify if…
The study lasts about one year. First, you'll receive the medication by IV infusion or shots under the skin for 12 weeks to see if it helps. If you respond well at week 12, you'll move into a maintenance phase where you'll receive injections every few weeks and be randomly assigned to one of two dosing schedules. Throughout the study, you'll have regular clinic visits, blood tests, and an endoscopy to check how your intestines are healing.
AI-generated summary from trial data · Aug 31, 2026 · Not medical advice
United States