Plain-English translation of NCT05931276 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether , a heart medication that is removed from your body during dialysis, works better than , another heart medication that stays in your body longer, for protecting your heart and helping you live longer. Both medications are already used to treat heart problems in dialysis patients, but doctors don't yet know which one is safer and more effective for you.
Veterans on dialysis have very high rates of heart disease and death, and while this medication is commonly prescribed, no one has directly compared which of the two most popular versions works best. Finding the right choice could significantly improve heart health and survival for dialysis patients.
You likely qualify if…
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You will be randomly assigned to take either or , with doses adjusted based on your current heart medication dose and your provider's judgment. Your doctor will monitor you during your regular dialysis appointments and follow-up visits to see how well the medication works for your heart health and to watch for any side effects.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
United States