Plain-English translation of NCT05932862 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is an early-stage trial testing a new experimental cancer medication called in people with advanced solid tumors. Researchers want to understand how safe the medication is, how your body processes it, and whether it helps shrink tumors. The medication will be tested both on its own and combined with another approved cancer drug called .
Many people with advanced cancers—especially those with specific genetic changes affecting DNA repair—have limited treatment options or stop responding to current therapies. This trial aims to determine whether this new medication could offer another treatment choice for these patients.
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The trial starts with a dose-escalation phase where you will receive increasing doses of the medication to find the safest effective dose, either alone or combined with . Later, once the best dose is determined, additional participants will receive that dose while researchers monitor how well it works for specific cancer types. You will have regular clinic visits for blood tests, imaging scans, and check-ins to track how you're responding and any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States