Plain-English translation of NCT05934305 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a therapy-based program called MATTER can help people living with HIV and substance use disorders stay on track with their HIV treatment. The program involves five one-on-one therapy sessions delivered online, plus personalized text messages to help you develop better coping skills and self-compassion. The goal is to help you overcome feelings of shame and stigma that might be getting in the way of taking care of your HIV.
Many people living with HIV who also have substance use challenges struggle to stay engaged in their HIV care because of internalized shame and stigma—negative feelings they have internalized about themselves. When people step back from their care, their HIV can become harder to control, which also increases the risk of passing HIV to others. This trial exists to test whether addressing these painful emotions directly through therapy can help people stay committed to their HIV treatment.
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If you join this study, you'll attend five one-on-one therapy sessions delivered over video call, where you'll learn skills like setting self-care goals, becoming more aware of your emotions without judgment, and practicing self-compassion. During and after these sessions, you'll also receive personalized text messages that check in on your emotions and send you encouraging messages. You may also receive help navigating resources you need (like treatment programs or medical appointments). The whole program lasts about 12 months, with follow-up visits to track how you're doing with your HIV care and viral control.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
United States