Ultrasound nerve treatment for high blood pressure in transplant patients

The RESTART study is testing renal sympathetic denervation—a minimally invasive ultrasound-based procedure that calms overactive nerves in your native (original) kidneys—to see if it can safely and effectively lower blood pressure in kidney transplant patients whose hypertension isn't controlled by medications alone. Researchers want to understand whether this treatment works differently in transplant patients compared to people without transplants, since the causes of high blood pressure may be unique in your situation.

High blood pressure is common and serious in kidney transplant recipients, and many people cannot control it with medication alone or cannot tolerate blood pressure drugs. This trial is the first to study whether this ultrasound nerve treatment is safe and effective specifically for transplant patients, filling an important gap since previous studies excluded people like you.