Plain-English translation of NCT05935124 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different ways doctors can look inside your colon during a screening colonoscopy: standard white light imaging and a newer technique called bright narrow band imaging. The study wants to find out which method helps doctors spot more precancerous polyps, especially the flat or harder-to-see ones that are often missed in the upper (right) part of the colon.
Current colonoscopy screening sometimes misses precancerous polyps in the right side of the colon, which can lead to cancer developing later. Researchers believe that the newer imaging technique might help doctors see these polyps better, but they need to test whether it actually works in a real screening setting.
You likely qualify if…
You likely don't qualify if…
You would undergo a standard screening colonoscopy, but the doctor would examine your right colon twice using two different imaging methods—one group starts with white light imaging followed by the newer bright narrow band imaging, while the other group has the order reversed. The colonoscopy itself follows the normal screening procedure, and you would not need additional visits or follow-up appointments beyond standard care.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
Australia
Sponsor
Western Sydney Local Health District
Enrollment target
~600 participants
Started
August 2015
Primary completion
May 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
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