Plain-English translation of NCT05935826 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Phase 3 โ Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether an Essential Amino Acid Supplement can help reduce the amount of fat stored in the liver in teenagers with fatty liver disease. Half of the participants will take the medication for 2 months, while the other half will take a placebo (a fake pill that looks identical). After 2 months, everyone in the study will have the option to continue and receive the actual medication for an additional 10 months.
Fatty liver disease in teenagers is becoming more common and there aren't many proven treatments available yet. Researchers think this medication might help because amino acids (the building blocks of protein) could help the liver process fat more effectively, but this needs to be tested carefully in young people.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You'll visit the research center at the start and end of the study to have an MRI scan (to measure liver fat), a body X-ray (to measure body composition), and a blood draw. During the 2-month treatment phase, you'll take either the medication or a placebo twice daily at home โ neither you nor the researchers will know which one you're taking. If you wish to continue, all participants then receive the actual medication for 10 additional months.
AI-generated summary from trial data ยท Jun 9, 2026 ยท Not medical advice
United States