Plain-English translation of NCT05937841 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Women who experience preeclampsia during pregnancy have a higher risk of heart disease later in life, even if they were otherwise healthy. This study uses a small skin test to examine how blood vessels function in women who had preeclampsia compared to those who had normal pregnancies. Researchers will apply a medication called to a tiny area of skin to see how blood vessels respond, which may help explain why preeclampsia increases heart disease risk.
Even after preeclampsia goes away after delivery, damage to blood vessel function can persist and lead to serious heart problems years later. Scientists don't yet understand exactly why this happens or how to prevent it. This study aims to identify the specific blood vessel problems that linger after preeclampsia so that better treatments can be developed.
You likely qualify if…
You likely don't qualify if…
You will visit the research clinic for a skin test using a minimally invasive technique called intradermal microdialysis. The researchers will place tiny delivery tubes into a small area of skin (about the size of a dime) and apply the test medications to see how your blood vessels respond. The visit will likely take a few hours, and you should expect some mild discomfort similar to a small injection.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
United States