Plain-English translation of NCT05939934 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a mandibular advancement device—a custom-fitted dental appliance that gently moves your lower jaw forward to keep your airway open during sleep—can help manage sleep apnea when you're not using your regular CPAP breathing machine. The study wants to understand if this device can reduce sleep apnea symptoms and improve your blood pressure and blood vessel health during a two-week break from your CPAP treatment.
Many people find their CPAP machines uncomfortable or difficult to use long-term, so doctors want to know if this treatment could be a helpful backup option or alternative when patients need a break from their regular therapy.
You likely qualify if…
You likely don't qualify if…
You would visit the sleep laboratory at Angers University Hospital for initial testing including blood pressure checks, blood and urine samples, heart rhythm tests, and blood vessel function studies. You would then be fitted with a custom dental device by a specialist, and asked to stop using your CPAP machine for two weeks while using only the dental device (or no treatment if you're in the comparison group). After two weeks, you would return for a one-night hospital stay where you'll have repeat testing and a sleep study wearing the dental device, after which you'll resume your regular CPAP use.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
France