Recruiting

Testing new quick tuberculosis diagnosis methods in clinics

Plain-English translation of NCT05941052 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing new, faster ways to diagnose tuberculosis using simple samples (like blood or saliva) that can be checked right in a clinic, rather than waiting days for traditional lab tests. The study will also ask healthcare workers how easy and practical these new tests are to use in real clinics.

About one in three people with tuberculosis around the world are never diagnosed or reported to health authorities. This study exists to find and validate faster diagnostic tests that can catch tuberculosis earlier, help people start treatment sooner, and reduce the spread of this disease.

Do you qualify?

You likely qualify if…

you are at least 12 years old and not hospitalized
you have had a cough lasting 2 weeks or longer, or you have risk factors for tuberculosis (like HIV infection, close contact with someone with TB, or a history of mining work) and tested positive on a TB screening
you have not completed tuberculosis treatment in the past 12 months
you live within 20 kilometers of the study clinic and can return for follow-up visits
you are willing to provide informed consent

You likely don't qualify if…

you have completed tuberculosis treatment within the past 12 months
you have taken antibiotics with anti-tuberculosis activity (including certain fluoroquinolones) in the past 2 weeks
you live more than 20 kilometers from the study site or cannot commit to follow-up visits
you are unwilling or unable to provide informed consent

What participation looks like

If you qualify, you will visit the clinic and provide samples (such as saliva or blood) for testing with the new diagnostic tests, which are quick and non-invasive. You will also have standard tuberculosis tests done so the researchers can compare how well the new tests work. Healthcare workers at the clinic will also be observed and surveyed about how easy the new tests are to use in everyday practice.

AI-generated summary from trial data · Jun 3, 2026 · Not medical advice

Trial locations(3 sites)

Nigeria

Zankli Research Center, Bingham University, Abuja

Philippines

De La Salle Medical and Health Sciences Institute, Dasmariñas

Zambia

Centre for Infectious Disease Research in Zambia, Lusaka