Plain-English translation of NCT05942027 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This study is testing whether adding Coenzyme Q10 to standard kidney disease treatment can help protect your kidneys and bones. You have chronic kidney disease — a condition where your kidneys are not filtering blood as well as they should — and your doctor has recommended treatment with a blood pressure medication called ramipril. This trial will compare how well ramipril works alone versus ramipril combined with a daily Coenzyme Q10 supplement over 6 months.
People with chronic kidney disease often develop bone problems and have dangerously high levels of a protein called phosphorus in their blood. Doctors want to know if this medication can help reduce these complications and slow kidney disease from getting worse, on top of what the standard blood pressure treatment already does.
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You will visit the clinic monthly for 6 months and receive weekly phone calls to check on how you are doing and whether you are taking your medications as prescribed. Half of participants will take ramipril plus a placebo (fake) pill, and half will take ramipril plus Coenzyme Q10 200 mg daily. The research team will measure your blood pressure, kidney function, and bone health markers at the beginning and end of the study to see if the supplement made a difference.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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