Plain-English translation of NCT05943457 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether Vitamin K2 (also called Menaquinone-7) can help reduce how often you have migraine headaches. Researchers have noticed that people with migraines often have stiffer arteries than people without migraines, and a lack of vitamin K2 might play a role in this. This study will see if taking this medication for 6 months can both decrease your migraine frequency and improve your blood vessel health.
Migraines are a major cause of disability, especially for women, and current treatment options don't work for everyone. This medication has shown promise in improving blood vessel health in other conditions, so researchers want to find out if it might help prevent migraines from happening as often.
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You will be randomly assigned to either take vitamin K2 or a placebo (a fake pill that looks identical) every day for 6 months. You'll visit the research clinic at the beginning, middle, and end of the study to have blood tests done and to have your artery stiffness measured. Throughout the 6 months, you'll keep a diary tracking your migraine days and symptoms so researchers can see if the medication helps reduce how often you get headaches.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Lebanon