Plain-English translation of NCT05945355 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether inspiratory muscle training—a type of breathing exercise using a handheld device called PrO2—can help children with asthma breathe better and control their symptoms. Researchers think that this kind of targeted breathing training might be especially helpful for children with asthma who also struggle with weight, because extra weight can make breathing problems worse. The study will compare children who do the breathing exercises with different levels of difficulty against children who use a practice device that doesn't provide real training.
Many children with asthma struggle with breathing, especially when they are overweight. Doctors think the problem may partly come from weak breathing muscles and small airway problems. This trial wants to see if strengthening the breathing muscles through targeted exercises could help these children feel better and have fewer asthma symptoms.
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You would visit the study clinic a few times over about 8 weeks. At the start, researchers will test how well your lungs work and measure your breathing strength. Then you'll be randomly assigned to one of three groups: one group will use the PrO2 breathing device at a lower challenge level, another group will use it at a higher challenge level, and a third group will use a practice device. You'll use your assigned device at home with the help of a smartphone app that guides you. Throughout the study, the research team will check in on how you're doing and how your asthma symptoms have changed.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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