Plain-English translation of NCT05945407 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing a hormone-based treatment (progestin therapy) to shrink early-stage womb cancer in women who want to preserve their ability to have children. Instead of the standard surgery that removes the uterus, participants receive medication aimed at achieving complete remission of the cancer while keeping the uterus intact. The study will follow women for five years to see how well this treatment works, how often cancer returns, and whether women are able to become pregnant.
Standard treatment for womb cancer involves removing the uterus, which ends a woman's ability to have biological children. This trial exists to test whether a gentler, medicine-based approach can work for younger women with very early-stage cancer who want to preserve fertility.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You will receive progestin (hormone) treatment designed to shrink your cancer, with the goal of complete remission within nine months. You'll have follow-up appointments every 3 to 6 months for five years, including imaging scans (MRI or ultrasound), blood tests, and possibly tissue samples to monitor your cancer status and overall health. The study will track whether your cancer goes away, whether it returns, and whether you are able to become pregnant after treatment.
AI-generated summary from trial data ยท Jun 19, 2026 ยท Not medical advice
China