Plain-English translation of NCT05946083 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers want to understand how binge drinking affects your gut bacteria and brain function — and whether taking a daily fiber supplement called inulin might help protect your brain. This is an important question because young adults who binge drink may experience changes in their gut bacteria that could affect how their brain works. The study will compare people who binge drink (some taking the supplement, some not) with people who drink little to no alcohol.
Binge drinking is common among college students, but we don't fully understand how it damages the brain or what might protect it. Recent research suggests that gut bacteria play a role in brain health, so this treatment may offer a new way to prevent brain damage related to heavy drinking.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll visit the research center for a clinical interview about your health history, take a brain scan (MRI) while doing some thinking tasks, and provide blood and stool samples. If you're in the binge-drinking group, you'll also take a daily fiber supplement (either inulin or a placebo) for several weeks. The whole study takes place over a few weeks and involves 1–2 visits to the hospital.
AI-generated summary from trial data · Sep 24, 2026 · Not medical advice
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