Testing digital tools to improve multiple sclerosis care

Plain-English translation of NCT05949580 on ClinicalTrials.gov ↗ · Source last updated January 2026 · Translation generated June 2026 · How we translate trials

What is this trial?

This study is testing whether two digital tools working together can improve how doctors care for people with relapsing-remitting multiple sclerosis. The first tool uses artificial intelligence to analyze your MRI brain scans and track subtle changes over time. The second tool is a smartphone app and doctor portal that lets you track your symptoms and medications, and helps your care team stay updated on your health between visits.

Doctors want better ways to catch early changes in multiple sclerosis and keep patients connected to their care team. This study is testing whether digital tools can help doctors spot disease progression earlier and give more personalized care.

Do you qualify?

You likely qualify if…

you have been diagnosed with relapsing-remitting multiple sclerosis for at least one year
you own a smartphone with Android 5.0 or newer, or iOS 11 or newer
you are willing and able to use a patient app regularly
you have a valid email address
your disability level is below 5.5 on the EDSS scale (a standard MS disability measure)
you have medical records available for at least one year before joining

You likely don't qualify if…

you have primary progressive or secondary progressive multiple sclerosis (instead of relapsing-remitting)
you are unable to have an MRI scan
you are currently enrolled in another clinical trial that tests new treatments
you have a medical reason that makes using the digital app unsafe

What participation looks like

You would download the icompanion patient app on your smartphone and use it regularly to log your symptoms, medications, and health updates. Your doctors would have access to this information through a secure portal, along with your MRI scans and brain imaging reports. You and your care team would fill out questionnaires about your health. The study involves about 500 people total, and your participation helps researchers understand whether these digital tools make MS care better and easier to manage.

AI-generated summary from trial data · Jun 10, 2026 · Not medical advice

Trial locations(5 sites)

United States

Minneapolis Clinic of Neurology, Golden Valley, Minnesota

Hackensack University Medical Center, Hackensack, New Jersey

Jersey Shore University Medical Centre, Neptune City, New Jersey

Germany

Universitaetsklinikum Carl Gustav Carus an der TU Dresden, Dresden

Praxis Dr. med. Max Deist und Michael Ernst ?Sinsheim, Sinsheim