Plain-English translation of NCT05956327 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers know that aerobic exercise can help people with schizophrenia feel better and think more clearly, and it may even change the shape of the brain in helpful ways. This study wants to understand *why* that happens by looking at genetic and brain changes in people who do three months of aerobic biking compared to people who do stretching and balance exercises.
Exercise seems to work well for schizophrenia symptoms, but scientists don't fully understand the biological mechanisms behind this benefit. By studying the genetic and molecular changes that happen during training, researchers hope to find better ways to help people with schizophrenia recover.
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You would be randomly assigned to either aerobic biking sessions or flexibility and balance training for three months. Throughout the study, researchers will take brain scans, measure how your symptoms change, test your memory and thinking, and collect information about genetic factors. The study includes baseline assessments, regular training sessions, and follow-up evaluations to track any changes in your brain structure and how you're feeling.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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