Plain-English translation of NCT05956951 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers have noticed that people with early schizophrenia have unusual sleep patterns and brain activity during sleep. This study tests whether playing gentle sounds during sleep—timed to match your brain's natural rhythms—can improve how your brain works and help with memory and thinking. You'll spend several nights in a sleep lab while researchers monitor your brain activity and test your memory before and after sleeping.
Sleep problems are common in schizophrenia and may be connected to thinking and memory difficulties. This treatment aims to restore normal sleep patterns, which could help improve symptoms and slow down how the illness progresses early on.
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You'll visit a sleep clinic at the hospital for four nights over about 3 weeks. On the first night, you'll get used to the sleep lab. On nights 2–4, you'll complete memory and thinking tasks before bed, then sleep while wearing sensors that monitor your brain waves. On some nights you'll receive gentle sound stimulation; on others, sham (fake) stimulation—you won't know which. The next morning, you'll repeat the thinking tasks. You'll also have a clinical evaluation, an IQ test, and complete a sleep quality questionnaire.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States