Recruiting

Using a breathing mask to reduce breathing problems in people with two lung diseases

Plain-English translation of NCT05958563 on ClinicalTrials.gov ↗ ·

What is this trial?

This trial is testing whether using a CPAP (continuous positive airway pressure) breathing mask can help people who have both COPD — a chronic lung disease that makes breathing difficult — and sleep apnea, a condition where breathing repeatedly stops during sleep. The study will follow 500 patients for one year to see if the CPAP mask reduces sudden flare-ups and worsening of symptoms compared to not using the mask.

Many people have both COPD and sleep apnea at the same time, which makes their breathing problems worse. Doctors aren't sure yet whether treating the sleep apnea with a CPAP mask can help prevent the serious flare-ups that happen with COPD, so this study aims to find out.

Do you qualify?

You likely qualify if…

you are 40 years of age or older
you have been diagnosed with COPD with confirmed airflow limitation
you have had at least one moderate to severe flare-up of your COPD symptoms in the past year
you have suspected sleep apnea based on screening questions
you have a confirmed sleep apnea diagnosis (moderate to severe) from an overnight sleep test
you have a working phone or tablet and are willing to use it during the study

You likely don't qualify if…

you have severe daytime sleepiness or have nearly had a car accident from falling asleep while driving in the past year
you have serious heart disease, including heart failure, severe irregular heartbeats, or recent stroke
you are already using oxygen therapy at home or a breathing machine
you have been previously diagnosed and treated for sleep apnea
you have a plan to have lung surgery or a lung rehabilitation program in the next year

What participation looks like

If you qualify, you will have an overnight sleep test to confirm your sleep apnea. Then you'll be randomly assigned to either use a CPAP breathing mask every night for one year, or to a control group that does not use the mask. You'll visit the clinic at 3, 6, 9, and 12 months for check-ups, breathing tests, and short walks to measure your exercise ability. The researchers will track how many times your COPD symptoms flare up and ask you questions about how you're feeling throughout the year.

Using a breathing mask to reduce breathing problems in people with two lung diseases

What is this trial?

Do you qualify?

What participation looks like

Trial locations(15 sites)