Plain-English translation of NCT05961124 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ovarian Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing , a maintenance medication that helps prevent ovarian cancer from coming back after initial chemotherapy. The study looks at whether starting patients at a lower dose and gradually increasing it helps reduce side effects and keeps more patients able to stay on the medication long-term. The research involves 40 women with advanced stage ovarian cancer who have already responded well to their first round of chemotherapy.
After chemotherapy, maintenance medications can help prevent cancer from returning, but they often cause serious blood-related side effects that force patients to take breaks or stop treatment altogether. This trial aims to find out whether a gentler dosing schedule—starting low and slowly increasing—might allow patients to stay on this medication longer without interruptions.
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You would take the medication by mouth each day, starting at a lower dose for the first two cycles, then increasing to a higher dose for cycles three and four. You would have weekly blood tests during your first month, then continue with regular blood work as scheduled. You would continue taking the medication at your personalized dose until either you experience a side effect requiring adjustment or your cancer shows signs of progression, which the study team will monitor closely.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
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