Plain-English translation of NCT05963191 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether the CAD-EYE system, an artificial intelligence tool that helps doctors spot polyps (precancerous growths) during colonoscopy, works as well as or better than a specialized dye technique for people with Lynch syndrome. Lynch syndrome is an inherited genetic condition that significantly increases your risk of colorectal cancer at a younger age. The study will compare how well each screening method detects polyps that need to be removed.
People with Lynch syndrome need very careful screening to catch cancer early, but the current gold-standard screening method using special dye is time-consuming and not widely available. This trial is testing whether the new AI technology could make screening easier, faster, and just as effective—or even better.
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You will come in for a standard colonoscopy screening visit. Beforehand, you will prepare your bowel using a special cleaning solution, just as you would for any colonoscopy. During the procedure, you'll be randomly assigned to either the new AI-assisted colonoscopy or the standard dye-based colonoscopy. Either way, any polyps found will be carefully documented and removed. The colonoscopy itself takes about 30 minutes, though you should plan for a few hours total including preparation and recovery time.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
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