Plain-English translation of NCT05965518 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is comparing two types of exercise programs for older adults (age 50+) living with HIV who have noticed some mild cognitive or memory changes. One group will do high-intensity interval training — short bursts of hard exercise followed by recovery periods — while the other group will do steady, moderate-intensity exercise for 12 weeks. The study wants to see which type of exercise better improves blood vessel health and brain function.
Older people living with HIV often experience problems with blood vessel stiffness and cognitive changes (like memory or thinking difficulties) as they age. Researchers want to find out if high-intensity exercise can address these problems more effectively than regular moderate exercise, so they can develop better ways to help this population stay healthy and independent.
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If you join this study, you will be randomly assigned to either the high-intensity interval training group or the moderate exercise group. You will exercise for 12 weeks as part of the study, and researchers will measure your blood vessel health and cognitive function before and after the program using standard medical tests. You may also be asked to talk about your experience with the exercise program and any barriers you faced.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States