Plain-English translation of NCT05967533 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing fermented wheat germ (FWG) as a daily nutritional supplement alongside your standard cancer immunotherapy. The researchers want to see if this supplement can help strengthen your immune system's natural ability to kill cancer cells, particularly by boosting a type of immune cell called NK cells. You would take the medication by mouth while also receiving your regular checkpoint inhibitor immunotherapy.
Some early evidence suggests that certain nutritional supplements might enhance the immune system's response to cancer treatment. This study exists to see whether this particular supplement actually helps patients receiving immunotherapy fight their cancer more effectively, and whether it's safe to take alongside standard treatment.
You would take the fermented wheat germ supplement by mouth once daily for 8 weeks, starting 3 days before your checkpoint inhibitor immunotherapy begins and continuing for 56 days. During the study, you would visit the clinic for blood draws at screening, and then on days 1, 4, 15, 43, and at the end of treatment; you would also provide stool samples at a few of these same visits. The study is designed to measure whether the supplement affects your immune system and to monitor for any side effects.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
United States