Plain-English translation of NCT05977283 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hepatitis B research guide →This is a three-year observational study following people with hepatitis B who have experienced a recent decline in their HBsAg levels (a marker that shows how much virus is in your blood). Researchers want to understand what happens to patients like you after your viral levels drop — whether you stay stable, improve further, or need additional care. Your doctor will continue managing your hepatitis B exactly as they normally would; this study simply tracks and documents your progress.
When hepatitis B patients experience a significant drop in their viral levels, doctors want to know whether this improvement lasts, what treatment patterns work best, and what long-term outcomes to expect. This study will help future patients by understanding these patterns better.
You likely qualify if…
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You will continue your normal hepatitis B care with your regular doctor — no extra procedures or medications required just for this study. Your doctor will continue monitoring you at their usual schedule (typically every 6 months, or more often if you're on certain medications), and they will simply document your routine test results and health information in a research database. This follow-up will continue for three years from when you enroll, and your doctor may extend your participation based on study goals.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
China
Sponsor
Nanfang Hospital, Southern Medical University
Enrollment target
~100 participants
Started
May 2023
Primary completion
June 2027
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in February 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Xieer Liang, M.D.
Nanfang Hospital, Southern Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.