Plain-English translation of NCT05978557 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to see if they can take a small piece of brain tumor removed during your surgery, grow it in the lab, and test it against different drugs to figure out which ones are most likely to help you. Right now, doctors don't have a reliable way to predict which drug will work best for each patient's brain tumor. This study explores whether this new testing method could give answers fast enough to actually guide your treatment decisions.
Brain tumors are very different from person to person, and doctors currently have no good way to know which drug will work best for each patient. This study aims to create a faster, more personalized way to predict which treatments are most likely to succeed for your specific tumor.
You likely qualify if…
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If you agree to participate, researchers will collect a small sample of your tumor tissue during your scheduled surgery—tissue that would otherwise be discarded. They will then grow this tissue in the lab and test it against various drugs to see which ones the tumor responds to best. The goal is to get these results back quickly so they can help inform your treatment plan.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States
Enrollment target
~50 participants
Started
July 2023
Primary completion
March 2028
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Devin McCarthy
UNC Lineberger Comprehensive Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.