Plain-English translation of NCT05979064 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a special tissue graft—harvested from fat in your abdomen using minimally invasive surgery—can be placed into the cavity left behind after removing a recurrent glioblastoma (a serious brain tumor). The idea is that this tissue graft may help deliver chemotherapy drugs and immune cells directly to where the tumor was, potentially making treatment more effective.
Glioblastoma is a very aggressive brain cancer, and when it comes back after initial treatment, options are limited. One major challenge is that the brain has a natural barrier that blocks many medications from reaching tumor cells. This trial explores whether the tissue graft can bypass that barrier and allow cancer-fighting treatments to work better.
You likely qualify if…
You likely don't qualify if…
If you qualify and join this trial, you would undergo planned surgery to remove your recurrent brain tumor. During that same surgery, your surgeon would also use a minimally invasive technique to harvest a small piece of fatty tissue from your abdomen, which would then be placed into the cavity left by the tumor removal. After surgery, you would have follow-up visits and MRI scans to monitor how you're healing and how well the graft is working.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Sponsor
Northwell Health
Enrollment target
~10 participants
Started
April 2023
Primary completion
April 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
John Boockvar, MD
Northwell Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.