Plain-English translation of NCT05981261 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how Parkinson's disease changes the way people experience pain. This study will carefully create temporary, mild pain in a laboratory setting—using heat, pressure, and a mild chemical irritant—and measure how people respond. By comparing healthy volunteers, people taking levodopa medication for Parkinson's, and people who have had deep brain stimulation surgery, the team hopes to learn whether Parkinson's affects pain perception.
Many people with Parkinson's disease report pain as a major symptom, but doctors don't fully understand why or how the condition changes pain processing in the body. This research could help doctors better recognize and treat pain in Parkinson's patients.
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You'll visit Aarhus University Hospital for one session lasting about 1.5 hours. During your visit, researchers will first ask about any ongoing pain you experience, then carefully test how your body responds to different types of pain—including brief exposure to heat, pressure on muscles, and a mild chemical irritant on the skin. They'll also measure how quickly your muscles respond to certain stimuli. All procedures are designed to be safe and temporary, and the research team will monitor you throughout.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
Denmark
Sponsor
University of Aarhus
Collaborators
Aarhus University Hospital
Enrollment target
~63 participants
Started
June 2023
Primary completion
January 2027
Last updated on clinicaltrials.gov in August 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Andrea Søndergaard Poulsen, PhD student
University of Aarhus
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.