How Cystic Fibrosis Medication Affects Nasal Health and Quality of Life

Researchers are studying how CFTR Modulator Therapy affects the sinuses and nasal health in adults with cystic fibrosis. This medication works by helping the faulty protein in CF work better, and the study wants to see how that change affects the bacteria living in your nose, inflammation levels, and your overall quality of life and ability to smell. By tracking these changes over two years, doctors hope to better understand how this treatment helps people with CF.

Many people with CF struggle with sinus problems, and researchers want to understand whether the newer CF medications are improving the environment inside the nose — including reducing harmful bacteria and inflammation — and whether these improvements are connected to how patients feel and their quality of life.