Plain-English translation of NCT05983432 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new medication called in people with advanced cancers that have spread or cannot be surgically removed. The study will evaluate whether the medication is safe, how well the body tolerates it, and whether it helps shrink tumors. You would receive the medication through an IV infusion either once or twice per three-week cycle, depending on which group you are assigned to.
Many people with advanced cancers need new treatment options because their cancer has stopped responding to existing therapies. This medication is being developed to offer hope to patients whose options have become limited.
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You would visit the study clinic every three weeks to receive an IV infusion of the medication. Depending on which study group you are assigned to, you would receive the infusion either once per cycle (on Day 1) or twice per cycle (on Days 1 and 8). Between visits, you would have blood tests and imaging scans to monitor how your body is responding and to check for side effects. The study has multiple phases to find the right dose and confirm the medication's safety and effectiveness.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States