Recruiting

Brain Education and Wellness Program for Migraine Relief

Plain-English translation of NCT05987592 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated June 2026 · How we translate trials

Read our Migraine research guide →

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing whether a structured online program called BE WELL With Migraine can help people who suffer from frequent migraines. The program includes 8 weekly virtual classes plus access to an online platform where you track your headaches and learn wellness strategies. Researchers want to see if this combination of education and self-care tools can reduce migraine frequency and improve your quality of life.

Many people with migraine struggle to manage their symptoms and find that treatment alone isn't enough. This program addresses that gap by combining education about how migraine affects the brain with practical wellness tools designed to help you feel more in control of your condition.

Do you qualify?

You likely qualify if…

you have been diagnosed with migraine (with or without aura) and experience 4–20 migraine days per month
you have had migraines for at least one year
you are at least 18 years old
you are able to attend 8 weekly online classes and complete daily headache logs
you are fluent in English and comfortable using online platforms
your migraine is affecting your daily life (measured by a simple screening score)

You likely don't qualify if…

you have a serious medical or mental health condition that is unstable or could make the group environment unsafe
you are overusing migraine medications or have recently started new migraine prevention treatments (within 12 weeks) or acute treatments (within 4 weeks)
you are more than 16 weeks pregnant at the time of enrollment
you have already tried stress-reduction training such as daily meditation, mindfulness apps, or MBSR classes
you have had a positive COVID-19 test within 30 days of enrollment

What participation looks like

You would participate entirely online from home—no in-person clinic visits required. After a brief phone or video call with the study team to get started, you'll attend 8 weekly virtual classes and use an online platform to log your daily headaches and complete surveys. The entire study takes about 8 weeks, and you'll need to keep taking your current migraine medications at the same dose throughout the program.

AI-generated summary from trial data · Jun 15, 2026 · Not medical advice

Trial locations(3 sites)

United States

Cambridge Health Alliance - Center for Mindfulness and Compassion, Cambridge, Massachusetts

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio