Plain-English translation of NCT05989386 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial compares two approaches to preventing infections after emergency abdominal surgery. One group receives a thorough saline (saltwater) rinse of the surgical wound before it is closed, while the other group receives standard wound closure without irrigation. Researchers want to see if this simple rinse reduces the rate of wound infections and shortens hospital stays.
Surgical wound infections are a common and serious complication after emergency abdominal surgery, leading to longer hospital stays and additional treatment. This trial tests whether a straightforward saline rinse during surgery could be a simple, low-cost way to prevent these infections.
You likely qualify if…
You likely don't qualify if…
If you qualify and agree to participate, you will be randomly assigned to receive either saline irrigation or standard care during your emergency abdominal surgery—the choice is made by chance, not by you or your doctor. After surgery, researchers will follow your recovery, track whether you develop any wound infections, and note how long you stay in the hospital. You will receive standard post-operative care and monitoring.
AI-generated summary from trial data · Aug 28, 2026 · Not medical advice
Pakistan
Phase
Large-scale testing
Sponsor
Dow University of Health Sciences
Enrollment target
~200 participants
Started
April 2023
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 60 Years
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Omer Bin Khalid, Assist Prof.
Dr. Ruth F. M. Pfau Civil Hospital Karachi
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.