Plain-English translation of NCT05989620 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is an observational study — meaning researchers will follow you over time and measure your muscle strength and function using standard clinical tests. The study includes people with different types of rare muscular dystrophy: limb girdle muscular dystrophy (LGMD), myotonic dystrophy type 2, and late-onset Pompe disease. By tracking how these conditions progress in many patients, researchers hope to better understand the diseases and speed up the development of new treatments.
Muscular dystrophies are rare diseases, and doctors don't have enough detailed information about how they progress in patients over time. This makes it harder to develop and test new treatments. This study will create a clear picture of how these conditions develop so that future clinical trials can be designed more effectively.
You likely qualify if…
You likely don't qualify if…
You will visit the research clinic regularly for clinical assessments that measure your muscle strength and function — these are standard tests that your doctor may already perform. The study will track these measurements over time so researchers can understand how your condition progresses. The visits and specific tests will depend on your condition type, but the overall goal is to collect consistent, detailed information about how muscular dystrophy develops across many patients.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States
Sponsor
Virginia Commonwealth University
Collaborators
Muscular Dystrophy Association
Enrollment target
~1,000 participants
Started
October 2023
Primary completion
October 2028
Age range
6 Years – 50 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jennifer Raymond
Virginia Commonwealth University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.