Plain-English translation of NCT05990244 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new imaging technique called Magnetic Resonance Elastography (MRE) that measures how stiff or firm a brain tumor is. Researchers believe that understanding tumor stiffness — along with genetic information from the tumor — can help doctors better classify the cancer, predict how it will behave, and improve treatment planning. The study will combine this new imaging with surgery and genetic testing to see if tumor stiffness can predict survival and treatment outcomes.
Currently, doctors can see brain tumors on standard imaging, but they cannot easily tell how firm or stiff the tumor is or how well it sticks to healthy brain tissue. Understanding these physical properties may help doctors predict which patients will do better or worse after treatment, and may guide decisions about how aggressively to treat the cancer.
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If you join this study, you will have a special MRI scan called Magnetic Resonance Elastography performed within one week before your scheduled brain surgery. During surgery, your surgeon will assess how stiff and sticky your tumor is and record those observations. After surgery, your tumor tissue will be sent for genetic testing to identify specific mutations. You will then receive standard treatment for your cancer type and be followed long-term so researchers can track your recovery and survival.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
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