Plain-English translation of NCT05991700 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing anthocyanin-rich table grape powder to see if it can prevent a common complication called post-operative atrial fibrillation—an irregular heartbeat that sometimes happens after heart surgery. You would take the grape powder or a placebo (inactive powder that looks the same) for a period before and after your heart valve surgery. Researchers want to understand whether this natural supplement might protect your heart's rhythm during recovery.
Irregular heartbeats are a frequent and serious problem that develops in some patients after heart surgery, which can lead to longer hospital stays and other complications. This study aims to see whether this medication might be a safe, natural way to reduce that risk.
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If you enroll, you would take either the concentrated grape powder or a matching placebo (fake powder) by mouth daily for a period before your scheduled heart valve surgery and continuing after. You would attend regular appointments at the Mitral Valve Clinic to take your assigned powder and have your heart monitored. The study tracks how many participants develop irregular heartbeats after surgery to see if the grape powder offers any protective benefit.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States