Plain-English translation of NCT05992870 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach to treating breast cancer that requires both surgery and radiation. Instead of the standard approach — removing the breast, placing an implant, and then giving radiation — researchers want to try giving radiation first, then doing the surgery and implant placement. The goal is to see if this order leads to better cosmetic results and fewer problems with the implant.
Radiation given after implant breast reconstruction can cause serious complications like implant failure, scarring, and the need for additional surgeries. Early research suggests that giving radiation before surgery might avoid these problems and help patients recover faster.
You would receive radiation therapy to your breast before your mastectomy surgery. After the radiation is complete, you would have surgery to remove the breast and place an implant for reconstruction. The study will track you after surgery to monitor how well you heal and watch for any complications. Researchers will compare your results to see if this approach leads to better outcomes than the standard method of doing radiation after surgery.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
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