Plain-English translation of NCT05995964 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atopic Dermatitis research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing two experimental medications called and to see if they can help people with moderate to severe atopic dermatitis (a long-lasting, itchy skin condition). The study will compare how well these medications work compared to a placebo (a fake treatment that contains no medicine). Researchers want to learn whether the medication is safe and effective for treating this skin condition.
Many people with moderate to severe atopic dermatitis do not get relief from creams and ointments applied to their skin. This study exists to test whether these new injectable treatments might offer a better option for people whose itching and rash are not controlled by standard topical treatments.
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Participants will receive multiple injections of either the study medication or a placebo during clinic visits over 12 to 13 weeks (or up to 10 months total, depending on which stage of the study they join). The study has multiple stages, and depending on which one you enter and how your skin responds, you may receive only the medication, only placebo, or placebo followed by the medication. Throughout the study, you will have regular visits to receive injections, have your skin examined, and complete blood tests to monitor your safety and response to treatment.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States