Plain-English translation of NCT06001619 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers are investigating how the bacteria living in your gut may influence prostate disease and how your body responds to prostate medications. This study will collect samples from men with benign prostate enlargement (being treated with finasteride, dutasteride, or a combination of dutasteride and tamsulosin) and men with prostate cancer (being treated with degarelix), to see if differences in gut bacteria help explain why some men develop prostate problems and why treatments work differently for different people.
Prostate cancer is very common in men, but doctors don't fully understand why some men develop serious disease while others don't—or why the same treatment works better for some patients than others. Recent research suggests that the trillions of bacteria living in your gut may play an important role in prostate health and how well medications work, but this hasn't been thoroughly studied yet.
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If you join this study, you'll provide stool and blood samples before you start your prostate medication, then again after 2 months of treatment. Your doctor will also measure your prostate size with ultrasound and check a blood marker called PSA at these visits. At 6 months, these same measurements will be repeated. The entire study lasts about 6 months, with visits spaced a few months apart.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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