Plain-English translation of NCT06002633 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing how alcohol affects decision-making and brain activity in adults with post-traumatic stress disorder (PTSD). Researchers want to understand why people with PTSD who drink alcohol may be at higher risk for developing alcohol use problems. The study will compare how the medication affects brain activity and choices in three groups: people with PTSD, people who experienced violence but don't have PTSD, and people without either condition.
Very little research has looked at how alcohol affects the brains and decision-making of people with PTSD specifically. Understanding this connection could help doctors develop better treatments to prevent alcohol problems in people with PTSD and improve overall outcomes.
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You will be asked to visit the research center multiple times over one year. During some visits, you'll drink a beverage containing either alcohol or a placebo (inactive comparison), while researchers monitor your brain activity using an MRI scanner and measure how you make decisions. You'll also complete questionnaires and interviews about your experiences, mood, and alcohol use. All visits will include arrangements for safe transportation home.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States