Plain-English translation of NCT06003036 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called accelerated intermittent theta burst stimulation (iTBS), which uses magnetic pulses to gently stimulate specific areas of the brain. Researchers want to see whether this brain stimulation can help improve thinking skills, memory, and attention in people with schizophrenia or schizoaffective disorder who are taking clozapine. The study will compare real brain stimulation to a sham (fake) version to understand whether the treatment actually works.
People with schizophrenia often experience problems with thinking, memory, and attention that can be hard to treat, even with medication like clozapine. Researchers hope that adding this type of brain stimulation might help improve these cognitive skills and enhance overall quality of life.
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You would start with a baseline evaluation and brain imaging scan (MRI). Then you would come in for two separate sessions: one where you receive the real brain stimulation and one where you receive sham stimulation. Each session includes another MRI scan. The order of these sessions will be randomly assigned, and neither you nor the researchers will know which is real and which is sham until the study is complete. The study focuses on safety and how the brain responds, rather than lasting weeks or months.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
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