Plain-English translation of NCT06022822 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether urolithin A, a supplement derived from pomegranate and other fruits, can help slow or prevent cancer cell growth in men with prostate cancer before they have surgery to remove their prostate. Researchers want to see if this medication reduces signs of cell damage and changes that are linked to cancer progression. Half of the participants will receive the real supplement, and half will receive a placebo (a dummy pill) over 3 to 6 weeks.
There is growing evidence that urolithin A may protect cells from damage and slow cancer growth, but this has not been fully tested in men with prostate cancer. This study aims to determine whether this medication actually works to reduce harmful cell changes before surgery removes the cancer.
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You will take either the supplement or a placebo pill by mouth twice a day for 3 to 6 weeks leading up to your scheduled prostate removal surgery. During this time, you will have blood samples taken at the start and end of the study. At the time of your surgery, doctors will also collect a small tissue sample from your prostate. The entire study takes just a few weeks and fits around your already-planned surgery.
AI-generated summary from trial data · Sep 11, 2026 · Not medical advice
United States